What Is Placenta Extract?

Placenta extract supplements have been a staple of Japanese beauty and wellness culture for decades, yet they remain something of a mystery to newcomers. At its core, placenta extract is a concentrated bioactive substance derived from the placenta — the organ that nourishes a developing fetus during pregnancy. The placentas used in supplements are typically sourced from pigs (porcine) or horses (equine), not humans, and undergo rigorous processing to isolate their beneficial compounds.

The placenta is extraordinarily rich in nutrients because its entire biological purpose is to sustain new life. This makes it a dense source of growth factors, amino acids, peptides, nucleic acids, vitamins, and minerals — all of which are of great interest in the beauty and wellness space.

Types of Placenta Supplements

Placenta supplements come in several forms, each with its own advantages:

  • Oral supplements (tablets/capsules): The most common form. Easy to incorporate into a daily routine and offer systemic absorption through the digestive tract.
  • Drinkable ampoules: Liquid concentrates that are popular in Japan and Korea. Often combined with collagen, hyaluronic acid, or vitamin C.
  • Injectable formulations: Medical-grade applications administered by licensed practitioners. Commonly used in anti-aging clinics in Japan.
  • Topical creams and serums: Applied directly to the skin. Useful for targeted skincare benefits, though molecular size can limit deeper penetration.

Porcine vs. Equine Placenta: What's the Difference?

Feature Porcine (Pig) Equine (Horse)
Source Pig placenta Horse placenta
Common use Oral supplements, skincare Oral supplements, injectables
Amino acid profile High, similar to human High, with unique growth factors
Popular in Japan, Korea, Taiwan Japan (particularly clinics)

Key Bioactive Components

What makes placenta extract valuable is its complex composition. Key components include:

  1. Growth factors: Proteins that signal cells to repair and regenerate. EGF (Epidermal Growth Factor) is among the most studied.
  2. Amino acids: The building blocks of proteins, essential for collagen synthesis and cellular function.
  3. Nucleic acids (DNA/RNA): Support cellular metabolism and may promote cell turnover.
  4. Vitamins and minerals: Including B vitamins, vitamin E, iron, and calcium.
  5. Hyaluronic acid: A natural moisture-binding compound already found in the skin.

How to Choose a Placenta Supplement

Not all placenta supplements are created equal. When evaluating options, consider the following:

  • Source transparency: Look for brands that clearly state whether their extract is porcine or equine, and where it is sourced.
  • Processing method: Enzymatic hydrolysis tends to preserve more bioactive compounds than harsh chemical extraction.
  • Concentration: Higher milligram counts don't always mean better quality — bioavailability matters more than raw quantity.
  • Additional ingredients: Many quality supplements combine placenta extract with collagen, vitamin C, or hyaluronic acid for synergistic effects.
  • Third-party testing: Reputable products undergo quality verification for purity and contaminant screening.

Who Are Placenta Supplements For?

Placenta supplements are primarily aimed at adults interested in supporting skin health, reducing visible signs of aging, and promoting overall wellness from within. They are particularly popular among those in their 30s and beyond, when the skin's natural collagen production and cellular repair capacity begin to slow. As with any supplement, individuals who are pregnant, nursing, or managing a health condition should consult a healthcare professional before beginning use.